Niklas Abraham

Simulation Technology Student @ University of Stuttgart

I am a bachelor’s student in Simulation Technology at the University of Stuttgart. As part of my studies, I have taken various modules in mathematics, including Calculus 1, 2, and 3, functional calculus, and numerical mathematics. In physics, I have completed courses in experimental physics and an introduction to quantum physics, among others. For my electives, I have focused on AI and bioinformatics courses.

Currently, I am working as a research student at the Institute of Biochemistry and Technical Biochemistry, under the supervision of Prof. JĂĽrgen Pleiss. My work involves the Python Enzyme Engineering Database (PyEED), a Python package we are developing for protein analysis. PyEED is built on Neo4J and facilitates the creation of networks for proteins, DNA, and ontologies. Currently, I am using PyEED to investigate TEM-Lactamase proteins.

In my future research, I hope to continue studying TEM proteins and further explore the use of graph databases and vector embeddings for ontologies in bioinformatics.

Outside my academic work, I am an indoor climbing instructor at a local climbing gym and enjoy training for upcoming triathlon events, which I am very passionate about. In my remaining free time, I read extensively and try to consume as much non-fiction as possible.

News

Oct 31, 2024 Attended “SAM-Enzyme conference” at the University of Stuttgart. Here, I had my first interaction with many experimental biochemists and learned firsthand about the problems of research software development.
Oct 31, 2024 Attended “Workshop on Large Language Models for Knowledge Engineering” at the University of Stuttgart. Here I was able to learn new and existing things about LLMs and onotlogy vector embeddings. I am looking forward to using hyperbolic geometry and poincaré embeddings in our research in pyeed.

Selected Publications

  1. Design and Realization of a Fast Optimal Transform
    Niklas Abraham
    2024